↓ Skip to main content

Camelid and shark single domain antibodies: structural features and therapeutic potential

Overview of attention for article published in Current Opinion in Structural Biology, November 2016
Altmetric Badge

About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (82nd percentile)
  • Good Attention Score compared to outputs of the same age and source (79th percentile)

Mentioned by

twitter
3 X users
patent
17 patents

Citations

dimensions_citation
156 Dimensions

Readers on

mendeley
254 Mendeley
citeulike
2 CiteULike
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Camelid and shark single domain antibodies: structural features and therapeutic potential
Published in
Current Opinion in Structural Biology, November 2016
DOI 10.1016/j.sbi.2016.10.019
Pubmed ID
Authors

Doreen Könning, Stefan Zielonka, Julius Grzeschik, Martin Empting, Bernhard Valldorf, Simon Krah, Christian Schröter, Carolin Sellmann, Björn Hock, Harald Kolmar

Abstract

In addition to canonical antibodies composed of heavy and light chains, the adaptive immune systems of camelids and cartilaginous fish comprise heavy-chain only isotypes (HcAb) devoid of light chains, where antigen-binding is mediated exclusively by one variable domain. Due to their inherent favorable attributes, such as high affinity and specificity for their cognate antigen, extraordinary stability, small size and, most importantly, the possibility to complement classical antibodies in terms of 'drugable' target-space, HcAb-derived entities evolved as promising candidates for biomedical applications of which many have already proven to be successful in early stage clinical trials.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 254 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Japan 1 <1%
Spain 1 <1%
Czechia 1 <1%
Brazil 1 <1%
Unknown 250 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 41 16%
Researcher 38 15%
Student > Bachelor 36 14%
Student > Master 26 10%
Student > Doctoral Student 10 4%
Other 31 12%
Unknown 72 28%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 74 29%
Agricultural and Biological Sciences 36 14%
Immunology and Microbiology 17 7%
Chemistry 10 4%
Medicine and Dentistry 8 3%
Other 29 11%
Unknown 80 31%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 11. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 December 2023.
All research outputs
#3,343,061
of 25,374,647 outputs
Outputs from Current Opinion in Structural Biology
#267
of 2,067 outputs
Outputs of similar age
#49,986
of 288,245 outputs
Outputs of similar age from Current Opinion in Structural Biology
#8
of 39 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. Compared to these this one has done well and is in the 86th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,067 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.7. This one has done well, scoring higher than 86% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 288,245 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 82% of its contemporaries.
We're also able to compare this research output to 39 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 79% of its contemporaries.